Human-GEM User Guide

Important

This guide applies to Human-GEM version v1.12.0. If you are using a different version of Human-GEM, we cannot guarantee that it will function as described in this guide.

Overview

This guide contains instructions and examples of how to use Human-GEM, a human genome-scale metabolic model (GEM). Choose a section from the sidebar or the list below to get started!

• Installation
• Getting started
• Flux balance analysis
• GEM extraction using ftINIT
• GEM comparison
• GEM extraction from single-cell RNA-Seq data
• Gene essentiality with DepMap
• Additional tools
• FAQs and troubleshooting
• Contact

Citation

J. L. Robinson, et al. An atlas of human metabolism. Sci. Signal. 13, eaaz1482 (2020). doi:10.1126/scisignal.aaz1482